Review Article
Pro-angiogenic and Angiostatic Compounds from Terrestrial and Marine Sources
Pankaj G* | |
Assistant Professor, School of Medical & Allied Sciences, K. R. Mangalam University, Sohna Road, Gurgaon-122103, Haryana, India | |
Corresponding Author : | Pankaj G Assistant Professor, School of Medical & Allied Sciences K. R. Mangalam University, Sohna Road Gurgaon-122103, Haryana, India Tel: 9818256122 E-mail: gupta.aiims@gmail.com |
Received May 23, 2014; Accepted July 27, 2014; Published July 29, 2014 | |
Citation: Pankaj G (2014) Pro-angiogenic and Angiostatic Compounds from Terrestrial and Marine Sources. J Homeop Ayurv Med 3:161. doi: 10.4172/2167-1206.1000161 | |
Copyright: © 2014 Pankaj G. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original author and source are credited. |
Abstract
The formation of new blood vessels out of pre-existing capillaries or angiogenesis is a sequence of events that is of key importance in a broad array of physiologic and pathologic processes. In several diseases, excessive angiogenesis is a part of the pathology such as cancer (both solid and hematologic tumors), cardiovascular disease (atherosclerosis), chronic inflammation (rheumatoid arthritis, Crohn’s disease), diabetes (proliferative diabetic retinopathy), neovascular wet age related macular degeneration, retinopathy of prematurity, psoriasis, andAIDS complications. These diseases may benefit from the therapeutic inhibition of angiogenesis. There has been a substantial progress made in research on natural products possessing several therapeutic actions as a result of which they have attracted attention of scientists, the world over and has profoundly influenced the course of discovery from traditional remedies. The present review entails such natural products from terrestrial and marine sources that have exhibited pro-angiogenic or antiangiogenic effects and offer subsequent potential for the development of novel pharmacological agents in the near future.