Journal of Infectious Diseases & Therapy
Open Access

Research Article

Prevalence of Substance Dependence among Susceptible TB Patients in a Private Sector Hospital in Karachi, Pakistan

Sara Khan^1*, Zainab Barry², Salman Khan¹, Ata-ur-Rehman² and Naveed Ali Khan²

¹The Indus Hospital, Karachi, Pakistan

²Interactive Research and Development, Pakistan

³Department of Surgery, Dow University of Health Sciences, Civil Hospital Karachi, Pakistan

*Corresponding Author:

Sara Khan
The Indus Hospital, Karachi, Pakistan
Tel: 0092-30025-72257
E-mail: sara.khan@industbcontril.org

Received date: June 15, 2016; Accepted date: July 21, 2016; Published date: July 25, 2016

Citation: Khan S, Barry Z, Khan S, Rehman AU, Khan NA (2016) Prevalence of Substance Dependence among Susceptible TB Patients in a Private Sector Hospital in Karachi, Pakistan. J Infect Dis Ther 4:290. doi:10.4172/2332-0877.1000290

Copyright: © 2016 Khan S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Background: Pakistan ranks sixth amongst the twenty-two TB high-burden countries in the world, accounting for one of the major health problems in Pakistan. Substance abuse is the most commonly reported behavioral risk factor among TB patients.

Objective: The objective of this study was to find out substances TB patients use frequently.

Study design: Retrospective Analytical study.

Methodology: A retrospective review was performed to analyze substance dependence in TB patients at Indus Hospital. Data were collected from 1,234 newly enrolled adult patients counseled at baseline from February 2012 to February 2014. The patients were categorized as substance dependent if they were positive on three of the seven criteria within the same year as defined by Diagnostic Statistical Manual of Mental Disorder Text Revision (DSM IVTR). Tolerance, increased amount of substance and persistent desire or unsuccessful efforts to cut down or control substance use was observed in our patients.

Results: Out of the 1,234 TB patients 590 (48%) were males and 644 (52%) were females. Overall 20% (251/1,234) of patients reported taking different substances were categorized as substance dependent out of which 85% (214/251) were males while 15% (37/251) were females. Cigarette smoking (up to a pack/day) was the most common addiction among patients, higher in males 51% (105/214) compared to 4% (2/37) females. 10% (21/214) of males used Niswar (smokeless tobacco) compared to 4% (2/37) females. Ghutka was comparatively more common in females 24% (11/37) than males 9% (18/214). Chewable tobacco was used by 7% (14/214) males compared to 35% (16/37) females. 5% (11/214) males used pan compared to 2% (1/37) females. Alcohol and charas (hashish) were respectively used by 0.5% (1/214) males only. 21% (44/214) males were addicted to multiple substances compared to 11% (5/37) females. The Indus Hospital provided special counseling to these patients about adverse reactions of substance on TB treatment and general health to ensure treatment compliance.

Conclusion: TB and substance abuse programs need to work hand in hand since substance abuse is associated with negative treatment outcomes. Effective interventions need to be developed by TB programs to address the need of patients who indulge in substance abuse.

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