Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Predictors of early onset neonatal sepsis among neonates in Dodoma, Tanzania: A case control study - Pendo Paschal Masanja - University of Dodoma

Abstract

Background: Early onset neonatal sepsis contributes significantly to the burden of neonatal morbidity and mortality in the first week of life. In Tanzania, neonatal sepsis accounts for 32% neonatal illness and leads to 29% of newborn deaths yearly. The objective of the study was to assess predictors of early-onset neonatal sepsis among neonates. Methods: A hospital based case-control study of randomly selected 105 cases and 217 controls in 3 hospitals in Dodoma region. Cases were neonates diagnosed with neonatal sepsis and controls were neonates without neonatal sepsis. Controls were matched to the cases by mother’s age and parity at a ratio of 1 case to 2 controls.

 

A semi-structured questionnaire was used to collect information about the potential predictors; including maternal and neonatal factors as well as intrapartum emergency interventions. Descriptive and inferential statistical analyses were employed to measure the independent association between independent variables and the outcome of interest. Results: Most (92.5%) of neonates were born at term and 7.5% were premature.

 

Average birth weight was 3 kilograms and 16% neonates had low birth weight (<2500 grams). Up to 33% of the newborns had early-onset neonatal sepsis. After adjusting for confounders, the maternal factors which showed significant association with early-onset neonatal sepsis were maternal history of chorioamnionitis [AOR=1.910,p=0.042,95%CI:1.022-3.56], HIV status [AOR=2.909,p=0.012,95% CI:1.020-8.296], prolonged rupture of membrane [AOR=2.857,p=0.014, 955CI: 1.233-6.619] and multiple digital vaginal examinations during labor [AOR=5.178,p=0.026,95%CI: 1.220-21.986].Neonatal factors; perinatal asphyxia [AOR=6.781, p=0.006, 95%CI: 1.725- 26.652].

 Conclusion: Maternal infection(s), obstetric complications and substandard procedures during labor and delivery have significant effects on the occurrence of early-onset neonatal sepsis. Prevention of early-onset neonatal sepsis could be achieved by addressing maternal obstetric and neonatal related conditions.

Keywords

Recommended Conferences
Google Scholar citation report
Indexed In
  • Google Scholar
  • ICMJE
Share This Page
Top