Abstract

Population pharmacokinetics is a specialized field within pharmacokinetics that focuses on understanding the variability in drug concentrations among individuals within a population. By employing mathematical models, population pharmacokinetics characterizes how drugs are absorbed, distributed, metabolized, and excreted in diverse patient groups. This approach plays a crucial role in drug development, personalized medicine, and pharmacovigilance, offering insights into optimizing drug dosing regimens and enhancing therapeutic outcomes while minimizing adverse effects. This article provides an overview of population pharmacokinetics, discussing its applications, modeling techniques, challenges, and future directions in pharmaceutical research and clinical practice.