Abstract

The Mariana Trench, plunging down to nearly 36,000 feet below sea level, is the deepest part of the world's oceans. This abyssal environment, characterized by crushing pressures, frigid temperatures, and perpetual darkness, might seem inhospitable to life. Yet, the trench is home to a remarkable array of microorganisms, among the most intriguing of which are piezo extremophiles. These extraordinary organisms have adapted to thrive under the extreme pressure conditions of the deep sea, offering insights into the limits of life on Earth and potential applications in science and industry