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Hindi Phytochemical Investigation of Bioactive Components from the Stem Bark of Syzygium guineense for Antibacterial and Antioxidant Conducts
*Corresponding Author:Received Date: Mar 19, 2024 / Published Date: May 01, 2024
Citation: Begeno TA, et al. (2024) Phytochemical Investigation of Bioactive Components from the Stem Bark of Syzygium guineense for Antibacterial and Antioxidant Conducts. J Mol Pharm Org Process Res 12: 225.DOI: 10.4172/2329-9053.1000225
Copyright: © 2024 Begeno TA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Plants provide numerous benefits, like medicine, food, shelter, clothing, fuel wood, and building materials. They contribute to soil fertility, recycle ecosystem nutrients, and protect water catchment regions. Phytochemicals produced by plants provide health benefits beyond macronutrients and micronutrients. Primary metabolites contain natural sugars, amino acids, proteins, and purines, while secondary metabolites protect plants from environmental hazards and diseases. Reports reveal metabolites from S. guineense organs, including isoprenoids, arjulonic acids, and asiatic acids. This study aimed to investigate different bioactive constituents’ different extraction methods using ethanol as solvent, namely: reflux extraction, ultrasonication extraction, and maceration extraction, using high-resolution UPLCMS techniques. The stem bark extract of S. guineense showed promising activity against S. aureus and E. coli, but as time intervals increased, the bacterial strain became more resistant. The extracts also showed DPPH radical scavenging action, with R values of 0.9972, indicating their potential as natural medicinal compounds for antioxidant and antibacterial disease management.
