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Hindi Pediatric Acute Promyelocytic Leukemia Presenting as Tongue Chloroma: Case Report
*Corresponding Author:Received Date: Jun 29, 2020 / Published Date: Sep 22, 2022
Copyright: © 2022 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Chloroma is a rare extramedullary tumor consisting of immature myeloid cells. Occurring in 1%-2% of patients with Acute Myelogenous Leukemia (AML). In a significant proportion of cases, it displays myelomonocytic or pure monoblastic morphologic features, which correlate with the French-American-British (FAB) classification of AML M4 and M5 respectively. Cytogenetically, chloroma occurs in association with a variety of chromosomal abnormalities, including MLL rearrangement in V and T. Usual sites include the skin, soft tissue and lymph nodes. Tongue chloroma is extremely rare. Here we report a case of pediatric Acute Promyelocytic Leukemia (APL) presenting with tongue chloroma. Furthermore, the prevalence of myeloid sarcoma of the spine was 1.0% among all patients with acute and chronic myeloid leukemia.
