Journal of Alzheimers Disease & Parkinsonism
Open Access

Review Article

Parkinson's Disease (Pathogenesis and Its Management): An Overview

Kumar BNP¹, Naresh Korrapati^2*, Shabana Kouser Ali³and Shaik Mohammed Irshad²

¹Livestock Research Institute, College of Veterinary Science, SVVU, Hyderabad, India

²Department of Biotechnology, Sri Krishna Devaraya University, Anantapur, India

³Department of BioInformatics, VIT, Tamil Nadu, India

*Corresponding Author:

Naresh Korrapati
Department of Bio-Technology
Sri Krishna Devaraya University
College of Engineering and Technology
Sri Krishna Devaraya University, Anantapur
Andhra Pradesh, India
Tel: +91-9492654991
E-mail: korrapatinaresh991@ gmail.com

Received date: October 13, 2016; Accepted date: November 07, 2016; Published date: November 14, 2016

Citation: Kumar BNP, Korrapati N, Ali SK, Irshad SM (2016) Parkinson’s Disease (Pathogenesis and Its Management): An Overview. J Alzheimers Dis Parkinsonism 6: 284. doi: 10.4172/2161-0460.1000284

Copyright: © 2016 Kumar BNP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Parkinson’s disease (PD) is an idiopathic neurodegenerative disorder which has its incidence mainly in elderly aged humans. Loss of dopaminergic neurons especially in the substantia nigra, presence of α-synuclein Lewy bodies, mitochondrial dysfunction are the main pathological implications that plays pivotal role in both sporadic and familial forms of the disease. As PD affects older adults mostly in economically developed countries and worldwide aging populations there is an urgent need to develop strategies for the health care of individuals with PD. Epidemiological studies help in better understanding of the risk factors for PD and also helps in management of the disease and effective planning of medical services. In this present review article current understanding of Pathophysiology, Risk factors of PD were presented and the latest therapeutic approaches were discussed.

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