Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi ORF3a mutations: an adaptive advantage for SARS-CoV-2 pathogenecity
*Corresponding Author:
Copyright: © 2020 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The outbreak of severe acute respiratory syndrome in November 2019 resulted in a global public health emergency which warrants investigation of the virulence and pathogenecity of SARS-CoV-2. The reasonably higher mutation rate in SARS-CoV-2 led to the emergence of its numerous genetic variants which is likely to be responsible for COVID-19 associated morbidity and mortality. Mutations in ORF3a protein could modulate viral pathogenecity by interfering with host immune response and apoptotic pathways.
