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No Association between Chronic Osteomyelitis and Parkinson's Disease in Older People in Taiwan
Shih-Wei Lai1,2, Juhn-Cherng Liu1,3, Chun-Hung Tseng1,4, Chih-Hsin Muo5,6 and Kuan-Fu Liao7,8*
2Department of Family Medicine, Taiwan
3Department of Radiology, Taiwan
4Department of Neurology, Taiwan
5Department of Public Health, Taiwan
6Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan
7Graduate Institute of Integrated Medicine, and China Medical University, Taichung, Taiwan
8Department of Internal Medicine, Taichung Tzu Chi General Hospital, Taichung, Taiwan
- Corresponding Author:
- Kuan-Fu Liao
Department of Internal Medicine, Taichung Tzu Chi General Hospital
No.66, Sec. 1, Fongsing Road, Tanzi District
Taichung City, 427, Taiwan
Tel: 886-4-2205-2121
Fax: 886-4-2203-3986
E-mail: kuanfuliao@yahoo.com.tw
Received date: April 02, 2013; Accepted date: May 18, 2013; Published date: May 22, 2013
Citation: Lai SW, Liu JC, Tseng CH, Muo CH, Liao KF (2013) No Association between Chronic Osteomyelitis and Parkinson’s Disease in Older People in Taiwan. J Alzheimers Dis Parkinsonism 3:112. doi:10.4172/2161-0460.1000112
Copyright: © 2013 Lai SW, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The aim of this study is to explore whether chronic osteomyelitis is associated with an increased risk of Parkinson’s disease in older people in Taiwan. By using the database from the Taiwan National Health Insurance program, this case-control study consisted of 4686 subjects aged 65 years or older with newly diagnosed Parkinson’s disease as the case group and 18744 subjects without Parkinson’s disease as the control group. After adjusting for cofounding factors, multivariable logistic regression analysis showed no association between chronic osteomyelitis and Parkinson’s disease in both gender (odds ratio = 0.71, 95% CI = 0.37-1.36 in men, and odds ratio = 0.90, 95% CI = 0.45-1.83 in women, respectively). We conclude that no association can be detected between chronic osteomyelitis and Parkinson’s disease in older people in Taiwan.
