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N,N,N-Trimethyl Chitosan and Its Potential Bactericidal Activity: Current Aspects and Technological Applications

Débora P Facchi1, Suelen P Facchi1 and Alessandro F Martins1,2*

1Environmental Engineering Program, Federal University of Technology, Paraná, Brazil

2Materials Science & Engineering Program, Federal University of Technology, Paraná, Brazil

*Corresponding Author:
Alessandro F Martins
Postgraduate in Materials Science & Engineering Program
Federal University of Technology-Paraná (UTFPR-LD)
CEP 86036-370 Londrina-PR, Brazil
Tel: 55-43 96543830
E-mail: afmartins@utfpr.edu.br

Received date: July 19, 2016; Accepted date: August 04, 2016; Published date: August 08, 2016

Citation: Facchi DP, Facchi PF, Martins AF (2016) N,N,N-Trimethyl Chitosan and Its Potential Bactericidal Activity: Current Aspects and Technological Applications. J Infect Dis Ther 4:291. doi:10.4172/2332-0877.1000291

Copyright: © 2016 Facchi DP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

N,N,N-Trimethyl chitosan (TMC) is one of most important chitosan derivative with stronger bactericidal property. Currently, the TMC has been attracted considerable attention, because it contains quaternized ammonium moieties (-+N(CH3)3) in its network. Its cationic property leads to a renowned bactericidal power. Besides, TMC has appropriate biocompatibility, biodegradability, mucoadhesive capacity and greater solubility at pH close to physiological condition regarding chitosan. In this way, there are not sources regarding revision papers toward TMC bactericidal action. So, this revision work reports the TMC potential to be applied in many fields, depicting its bactericidal performance, as well as, its bactericidal mechanism and some current technological aspects that must be considered.

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