Abstract

Sleep as a widespread physiological phenomenon is seen in all vertebrates. In primates as human, the sleep consists of two components Rapid eye movement (REM) & non-REM. One of the major centers involved in the control of REM sleep is Locus Coeruleus (LC). REM sleep deprivation causes neural death in the LC. In the present study, we administered melatonin as an antioxidant factor and neuroprotective agent to prevent neural death.

Keywords: RSD, REM, Non-REM