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Neuroblastoma in the Adult: Which Therapy is Effective?
| Feryal Karaca1, Çiğdem Usul Afşar2*, Meral Günaldı2, and Berksoy Şahin2 | |
| 1Department of Radiation Oncology, Cukurova University Medical Faculty, Adana, Turkey | |
| 2Department of Medical Oncology, Cukurova University Medical Faculty, Adana, Turkey | |
| Corresponding Author : | Çiğdem Usul Afşar, MD Department of Medical Oncology Çukurova University Medical Faculty Balcali Hospital, Adana, Turkey Tel: +903223386060 (3142) E-mail:cigdemusul@yahoo.com |
| Received June 19, 2014; Accepted August 04, 2014; Published August 08, 2014 | |
| Citation: Karaca F, Afşar CU, Günaldı M, Şahin B (2014) Neuroblastoma in the Adult: Which Therapy is Effective? Clin Pharmacol Biopharm 3:119. doi:10.4172/2167-065X.1000119 | |
| Copyright: © 2014 Karaca F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
The examination of a twenty-eight-year-old male patient with lower back pain revealed a mass that extended through the spinal canal at the L1-L2 level and exhibited left paravertebral extension which was indistinguishable from the psoas muscle. Neuroblastoma was diagnosed after performing a biopsy. The disease progressed in that same year and in the following years, even after performing surgery, radiotherapy, chemotherapy, and bone marrow transplantation. The course of the disease was resistant to different high-dose chemotherapies and radiotherapy. The patient died four years after diagnosis. Neuroblastoma, a tumor which more frequently appears in children, is seen as an advanced or metastatic disease in adults. Currently there is no standard treatment for neuroblastoma in adults. The treatment protocols applied in children are insufficient for adults. Generally neuroblastoma is characterized as a localized disease, but in adults it is more aggressive.
