Abstract

Addiction and drug abuse disorders are characterized by chronic relapses, making treatment challenging. Research into the neural mechanisms underlying addiction offers valuable insights into recovery and treatment outcomes. This article explores the neural pathways involved in addiction, emphasizing the role of key brain regions such as the prefrontal cortex, limbic system, and striatum. Additionally, we examine neuroplasticity in recovery, and how treatment approaches like cognitive-behavioral therapy (CBT), pharmacotherapy, and neuromodulation can modify these pathways. Understanding the neurobiological basis of addiction is essential for developing more effective therapeutic interventions, improving patient outcomes, and potentially preventing relapses.