Abstract

Neonatal neuroprotection is a critical field focused on safeguarding the developing brain of premature and at-risk infants from injury. With advances in neonatal care, various strategies have emerged to mitigate the impact of brain injury caused by conditions such as hypoxic-ischemic encephalopathy (HIE) and intraventricular hemorrhage (IVH). This article reviews current neuroprotective strategies, including hypothermia therapy, pharmacological interventions, and nutritional support, and discusses emerging therapies such as stem cell treatment and neurogenesis-promoting agents. We also explore the challenges and future directions in neonatal neuroprotection, emphasizing the need for personalized approaches and long-term outcomes assessment