ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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  • Mini Review   
  • J Infect Dis Ther,
  • DOI: 10.4172/2332-0877.1000514

Multidrug Resistant Bacterial Co-Infections in Critically Ill Patients with COVID-19: A Review after Three Years of Pandemic

Rosario Cultrera1*, Brunella Quarta2, Carlo Alberto Volta3, Diana Campioni4, Daniela Segala1, Roberto Pora4 and Savino Spadaro3
1Department of Infectious Diseases, University of Ferrara, Ferrara, Italy
2Department of Pharmacy Service, University Hospital of Ferrara, Ferrara, Italy
3Department of Intensive Care Unit, University of Ferrara, Ferrara, Italy
4Department of Biotechnology and Clinical Microbiology, University Hospital of Ferrara, Ferrara, Italy
*Corresponding Author : Dr. Rosario Cultrera, Department of Infectious Diseases, University of Ferrara, Ferrara, Italy, Email: ctr@unife.it

Received Date: Aug 11, 2022 / Published Date: Sep 16, 2022

Abstract

Secondary bacterial infections and co-infections frequently affect COVID-19 patients. However, bacterial coinfection rates increase in patients admitted in the Intensive Care Units (ICUs), and those diseases can be due to superinfections by Multidrug-Resistant (MDR) bacteria. Most of these infections are related to high-risk carbapenemase-producing clones and occasionally with resistance to new β-lactam-β-lactamase inhibitor combinations. This highlights the urgency to revise frequent and empiric prescription of broad-spectrum antibiotics in COVID-19 patients, with more attention to evidence-based studies and the need to maintain antimicrobial stewardship and infection control programs in pandemic crises. Additionally, the SARS-CoV-2 pandemic highlighted the challenge that an emerging pathogen provides in adapting prevention measures regarding both the risk of exposure to caregivers and the need to maintain quality of care.

Keywords: Secondary bacterial infections; COVID-19; Pandemic outbreak; Health Care; Bacteria

Citation: Cultrera R, Quarta B, Volta CA, Campioni D, Segala D, et al. (2022) Multidrug Resistant Bacterial Co-Infections in Critically Ill Patients with COVID-19: A Review after Three Years of Pandemic. J Infect Dis Ther 10:514. Doi: 10.4172/2332-0877.1000514

Copyright: © 2022 Cultrera R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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