Abstract

The development of symptoms over time is a major effect of bipolar disorder (BD). The Longitudinal Interval Followup Examination (LIFE), a retrospective interview, has a low evaluation burden despite its potential recall issues. In two clinical assessments spreading over eighteen months of psychotherapy for BD patients, this study looks at the connection between the survey LIFE scale and outlook rating scales. The LIFE was routinely administered, and the Youthful Insanity Rating Scale (YMRS) and Montgomery-Asberg Gloom Rating Scale (MADRS) were regulated every eight or nine weeks. At times that were related, we investigated the relationship between LIFE scores and mood rating scale scores. There was a strong correlation between LIFE ratings of mania and the YMRS score (r = 0.40), as well as a strong correlation between LIFE ratings of sadness and the MADRS score at the same time (r = 0.57). A receiver operating characteristics (ROC) analysis revealed that the LIFE scores that were applied to the MADRS in order to define "moderate depression" had an AUC of 0.78. Even when the LIFE rating was given months prior to the interview, the correlations were strong, especially for depression scores. This suggests that with little effort, the LIFE can accurately and efficiently assess the burden of mood symptoms over time. The connection between side effect weight and this sort of personal satisfaction estimation ought to be the essential focal point of ensuing examination.

Keywords: Bipolar Disorder; Mood Rating Scales; Longitudinal Assessment; Mood Assessment; Psychotherapy