Abstract

Vaginal drug delivery represents a promising avenue for the administration of therapeutics, offering several advantages over conventional routes such as oral or parenteral delivery. The vaginal route offers a unique environment characterized by its rich vascularization, permeability, and proximity to target tissues, making it an attractive site for drug absorption and localized therapy. Vaginal drug delivery holds particular relevance for the treatment of gynecological conditions, sexually transmitted infections, and reproductive health disorders. Various formulations have been developed to facilitate drug delivery via the vaginal route, including gels, creams, tablets, suppositories, and films. These formulations can be tailored to achieve sustained release, mucoadhesion, or targeted delivery to specific sites within the vaginal cavity. This abstract provides an overview of the key principles and advancements in the field of vaginal drug delivery.