Abstract

Metastatic osteosarcoma presents a significant challenge in pediatric oncology, with its aggressive nature and propensity for distant spread. This article provides an overview of the current understanding of metastatic osteosarcoma in pediatric patients and discusses key considerations in its management. Diagnostic evaluation, including imaging studies and biopsy, is crucial for early detection of metastatic disease. A multimodal treatment approach combining surgery, chemotherapy, and, in some cases, radiation therapy is typically employed. Emerging therapeutic strategies, such as targeted therapy and immunotherapy, show promise in improving outcomes. Psychosocial support is essential to address the emotional toll of the disease on patients and families. By implementing comprehensive management strategies, healthcare providers can optimize outcomes for pediatric patients with metastatic osteosarcoma