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Hindi Review Article
Low-level Laser Therapy Promotes Decrease in Inflammatory Process in Obese Trained Rats
de Aquino AE Jr.1,2*, de Castro CA3,4, Ana da Silva K3, Carbinatto FM1, Anibal FF2, Duarte ACGO3,4, Bagnato VS1,2 and Parizotto NA2,51Optics Group from Institute of Physics of São Carlos (IFSC), University of São Paulo (USP), São Paulo, Brazil
2Biotechnology Post Graduation Program, Federal university of São Carlos (UFSCar), São Paulo, Brazil
3Physiological Science Post Graduation Program, Federal University of San Carlos, São Paulo, Brazil
4Laboratory of Nutrition and Metabolism Applied to Exercise, Physical Education and Motor Human Department, Federal University of San Carlos (UFSCar), São Paulo,Brazil
5Electrothermophototherapy Laboratory, Department of Physical Therapy, Federal University of San Carlos, São Paulo, Brazil
- *Corresponding Author:
- Antonio Eduardo de Aquino Jr., PhD
University of São Paulo, Institute of Physics of São Carlos (IFSC)
Trabalhador São Carlense Avenue
400, Pq Arnold Shimidt, São Carlos, São Paulo, Brazil
Tel: 55 (016) 3373 9810
E-mail: antonioaquino@ursa.ifsc.usp.br
Received date: Feb 02, 2016; Accepted date: Apr 09, 2016; Published date: April 25, 2016
Citation: de Aquino AE Jr., de Castro CA, Ana da Silva K, Carbinatto FM, Anibal FF, et al. (2016) Low-level Laser Therapy Promotes Decrease in Inflammatory Process in Obese Trained Rats. J Community Med Health 6:414. doi:10.4172/2161-0711.1000414
Copyright: © 2016 Junior AEA, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
On present days, the obesity is present in 20% of the world. The combined use of low-level laser therapy and exercise may potentiate the effects promoted by exercise. The objective of this study was to investigate the conjugated effects of exercise and phototherapy on inflammatory markers. The 64 rats was used, which were divided into eight groups (n=8): normocaloric diet groups - sedentary normal diet; swimming trained normal diet; sedentary normal diet plus laser; swimming trained normal diet plus laser; and high-fat diet groups - sedentary highfat diet; swimming trained high-fat diet; sedentary high-fat diet plus laser; and trained high-fat diet plus laser . The rats were submitted to swimming training for 90 minutes/5 times per week for 8 weeks and low-level laser therapy (GA-Al-AS, 830 nm) at a dose of 4.7 J/point with a total energy of 9.4 J/animal, the point of application was gastrocnemius muscles after exercise. We observed alterations in inflammatory makers: reduction of IL-6 in the group sedentary normal diet versus swimming trained normal diet; and sedentary high-fat diet versus swimming trained high-fat diet; increase of IL-4 in the group sedentary normal diet versus swimming trained normal diet; reduction of TNF-α in the group sedentary normal diet versus and swimming trained normal diet; and increase sedentary high-fat plus versus sedentary high-fat diet plus laser; increase of IL-10 in the group sedentary normal diet versus swimming trained normal diet; and swimming trained high-fat diet versus trained high-fat diet plus laser; and reduction swimming trained normal diet versus swimming trained high-fat diet. All comparisons were significant to p<0.05. We concluded that this intervention promotes reduction of the inflammatory process. Thus, the reduction of the inflammatory process is extremely beneficial for the whole body.
