Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Research Article
Left Ventricular Non-Compaction: Mid-myocardial Distribution of Late Gadolinium Enhancement in Compacted Segments
Szemraj-Rogucka Z* and Majos A
Department of Radiology and Diagnostic Imaging, Central Clinical Hospital Medical, University of Lodz, Lodz, Poland
- *Corresponding Author:
- Zofia Szemraj-Rogucka
Department of Radiology and Diagnostic Imaging
Central Clinical Hospital Medical
University of Lodz
Lodz, Poland
Tel: 48512074680
E-mail: szemraj.zofia@gmail.com
Received Date: January 07, 2017; Accepted Date: January 07, 2017; Published Date: January 25, 2017
Citation: Szemraj-Rogucka Z, Majos A (2017) Left Ventricular Non-Compaction: Mid-myocardial Distribution of Late Gadolinium Enhancement in Compacted Segments. OMICS J Radiol 6:246. doi: 10.4172/2167-7964.1000246
Copyright: © 2017 Szemraj-Rogucka Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background: Cardiovascular Magnetic Resonance (CMR) with Late Gadolinium Enhancement (LGE) is a proven method for detecting myocardial fibrosis. Previous CMR studies described the distribution of LGE in patients with LVNC; however, it still remains unclear. The purpose of the study was to describe the distribution of LGE in patients meeting cardiovascular magnetic resonance criteria for Left Ventricular Non-Compaction (LVNC). Methods: We retrospectively enrolled 15 patients adult patients (11 males and 4 females; mean age, 42 ± 13 years) considered to meet standard CMR criteria for LVNC. For each patient, cine and contrast-enhanced CMR images were analyzed to evaluate LV systolic function and the prevalence and ex-tent of LGE. The presence or absence of LGE was qualitatively determined for each left ventricular myocardial segment. Results: The mean NC/C ratio was 4.6 ± 0.9. The areas of non-compaction were most commonly observed at the apex, the anterior and the lateral walls, mainly on their apical and mid-cavity segments. LGE was present in 11 of the 15 patients (73%). LGE was observed most frequently in the ventricular septum commonly on basal and mid-cavity segments. The distribution of LGE was midmyocardial (n=42; 67%), subepicardial (n=11; 18%), transmural (n=6; 10%) and subendocardial (n=3; 5%), in total of 62 LGE (+) left ventricular segments. No association was found between LGE and non-compaction at left ventricular segmental level (phi coefficient 0,021; p= 0.191). Conclusion: LGE was most often observed in the ventricular septum with mid-myocardial distribution. Distribution of LGE in patients with LVNC is observed in both non-compacted and compacted segments with prevalence of compacted zones. This maintenance the concept that LVNC is a diffuse process including both non-compacted and morphologically normal segments.
