Journal of Clinical & Experimental Pathology
Open Access

Case Report

Isolated Intracranial Rosai-Dorfman Disease Mimicking Convexity Meningioma: A Case Report

Tetsuro Sameshima^1*, Akio Morita¹, Rokuya Tanikawa², Toshiyuki Tsuboi² and Ryuhei Kitai³

¹Department of Neurosurgery, NTT Medical Center Tokyo, Tokyo, Japan

²Department of Neurosurgery, Abashiri Neurosurgical Hospital, Abashiri, Hokkaido, Japan

³Division of Neurosurgery, Department of Sensory & Locomotor Medicine, Faculty of Medical Science, University of Fukui, Fukui, Japan

*Corresponding Author:

Dr. Tetsuro Sameshima
Department of Neurosurgery
NTT Medical Center Tokyo
5-9-22, Higashi-Gotanda, Shinagawa-ku
Tokyo 141-8625, Japan
Tel: +81-3-3448-6111
Fax: +81-3-3448-6136
E-mail: tetsurosameshima@gmail.com

Received date: May 25, 2012; Accepted date: July 23, 2012; Published date: July 25, 2012

Citation: Sameshima T, Morita A, Tanikawa R, Tsuboi T, Kitai R (2012) Isolated Intracranial Rosai-Dorfman Disease Mimicking Convexity Meningioma: A Case Report. J Clin Exp Pathol 2:118. doi:10.4172/2161-0681.1000118

Copyright: © 2012 Sameshima T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract
Intracranial Rosai-Dorfman disease without systemic involvement is extremely rare. A 59-year-old woman
presented with headaches. Magnetic resonance imaging revealed an enhancing posterior fossa convexity lesion
with the dural tail sign. The preoperative diagnosis was meningioma. The histopathological examination revealed
reactivity for S-100 and CD68 and non-reactivity for CD1a with emperipolesis (lymphophagocytosis) characteristic of
Rosai-Dorfman disease.

Keywords