Abstract

Age-related cardiovascular diseases (CVDs) represent a significant health burden worldwide. Oxidative stress, a condition characterized by an imbalance between the production of reactive oxygen species (ROS) and the body’s antioxidant defense mechanisms, has been implicated in the pathogenesis of various CVDs. This review aims to elucidate the mechanisms by which oxidative stress contributes to the development and progression of age-related CVDs, including atherosclerosis, hypertension, and heart failure. We also explore potential therapeutic interventions targeting oxidative stress to mitigate these diseases.