Abstract

Inflammatory pain is a complex phenomenon that results from the body's immune response to injury or infection, leading to discomfort or distress in affected tissues. It plays a central role in various conditions, such as arthritis, infections, and autoimmune diseases. The pain is a consequence of the activation of inflammatory mediators and nociceptors, triggering both peripheral and central sensitization. This article reviews the mechanisms underlying inflammatory pain, its diagnostic challenges, and the current therapeutic approaches aimed at alleviating pain and inflammation. It also explores the future directions for improving treatment outcomes.