Abstract

This research aims to explore the intricate relationship between high-dose radiation therapy, alterations in brain structure, and subsequent implications for psychological well-being and cognitive functioning in patients undergoing treatment for brain tumors. While radiation therapy is a cornerstone in the management of brain tumors, its effects on the brain beyond tumor control have garnered increasing attention. The study will utilize neuroimaging techniques, psychological assessments, and cognitive testing to comprehensively evaluate changes in brain structure, psychological well-being, and cognitive function throughout the course of treatment. Findings from this research hold significant potential to inform clinical practice, improve patient care, and guide the development of interventions to mitigate adverse effects associated with radiation therapy.