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Intraosseous Malignant Peripheral Nerve Sheath Tumor of the Thoracic Spine: A Case Report and Review of Literature
Jung-Hee Lee and Chaisiri Chaichankul*Phramongkutklao College of Medicine, Bangkok, Thailand.
- *Corresponding Author:
- Dr. Chaisiri Chaichankul
Phramongkutklao College of Medicine
Bangkok, Thailand
E-mail: chaichankulc@yahoo.com
Received Date: February 22, 2016; Accepted Date: March 07, 2016; Published Date: March 13, 2016
Citation: Lee JH, Chaichankul C (2016) Intraosseous Malignant Peripheral Nerve Sheath Tumor of the Thoracic Spine: A Case Report and Review of Literature. J Orthop Oncol 2:107. doi:10.4172/2472-016X.1000107
Copyright: © 2016 Lee JH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
At the present time, only few reports including systematic reviews of malignant peripheral nerve sheath tumors (MPNSTs) with spinal involvement have been existed. Although there were reports of both MPNSTs of paraspinal soft tissue (type 1) resulting in secondary vertebral destruction and MPNSTs primarily originated from intraosseous of vertebra itself (type 2), these kinds of tumors are exceptionally rare. In this present report, we hereby demonstrated a case of type 2 MPNSTs which is not related to neurofibromatosis type 1 (NF 1) occurring in the thoracic spine and reviewed the clinical, radiologic, and pathologic as well as shared part of our experience in treating this rare condition. Interestingly, MPNSTs usually have a high rate of recurrence both local and metastasis even in the cases of successful en bloc resection with adjuvant therapy, but not in ours for 5-year follow up.
