World Journal of Pharmacology and Toxicology
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  • Review Article   
  • World J Pharmacol Toxicol 2022, Vol 5(4): 160
  • DOI: 10.4172/wjpt.1000160

Induced Pluripotent Stem Cell-derived Cardiomyocytes can serve as Acellular Models for Cardiac Toxicity Testing

Moyes Yuan*
National Laboratory of Bio-macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, China
*Corresponding Author : Moyes Yuan, National Laboratory of Bio-macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang, Beijing, China, Email: moyes.y@gmail.com

Received Date: Jul 23, 2022 / Published Date: Aug 23, 2022

Abstract

Induced pluripotent stem cell (iPSC) science is developing thrilling new possibilities for cardiovascular lookup by way of offering structures to learn about the mechanisms of ailment pathogenesis that ought to lead to new treatments or divulge drug sensitivities. In this review, the practicable usefulness of iPSC-derived cardiomyocytes in drug improvement as nicely as in drug toxicity checking out is discussed, with a center of attention on the achievements that have been already made in this regard. Moreover, the critical steps that have to be taken earlier than this science can be widely used in drug discovery and toxicology assessments are highlighted.

Citation: Yuan M (2022) Induced Pluripotent Stem Cell-derived Cardiomyocytes can Serve as Acellular Models for Cardiac Toxicity Testing. World J Pharmacol Toxicol 5: 160. Doi: 10.4172/wjpt.1000160

Copyright: © 2022 Yuan M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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