Abstract

Recent advancements in Nuclear Magnetic Resonance (NMR) imaging and spectroscopy have significantly enhanced our understanding of biological systems in vivo. This review highlights key developments that have improved the resolution, sensitivity, and applicability of NMR techniques in biomedical research. Innovations such as hyperpolarization, high-field magnets, and novel contrast agents have expanded the potential of NMR to provide detailed metabolic and structural information at the cellular and molecular levels. Additionally, integration with other imaging modalities, such as MRI, has enabled comprehensive, non-invasive analysis of physiological processes. These advancements are fostering new insights into disease mechanisms, drug efficacy, and personalized medicine, marking a new era in in vivo imaging and spectroscopy.