Impairment of Normal Endothelial Cell Function Plays a Major Role in the Initiation and Advancement of Cardiovascular Disease
Received Date: Mar 01, 2023 / Accepted Date: Mar 28, 2023 / Published Date: Mar 29, 2023
Abstract
Endothelial dysfunction is a significant factor in the development and progression of cardiovascular disease. Microparticles (MPs) derived from endothelial cells are considered to be biological markers of endothelial injury and repair, and could potentially serve as useful predictors of clinical outcomes. Apoptotic endothelial cell-derived MPs have been shown to contribute to microvascular inflammation and worsening of endothelial integrity, whereas endothelial MPs originating from activated endothelial cells may promote vascular repair and vasodilation.
Citation: Munawar S (2023) Impairment of Normal Endothelial Cell Function Plays a Major Role in the Initiation and Advancement of Cardiovascular Disease. Atheroscler Open Access 8: 197. Doi: 10.4172/asoa.1000197
Copyright: © 2023 Munawar S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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