Abstract

Breast-conserving surgery (BCS) is a widely accepted approach for the treatment of early-stage breast cancer. However, achieving clear surgical margins remains a challenge, leading to the necessity of re-excision in certain cases. This study aims to investigate the influence of re-excision on overall survival in a large population-based cohort of breast cancer patients who underwent BCS. Using data from [insert specific database or registry], we conducted a retrospective analysis of [insert number] patients diagnosed with early-stage breast cancer who underwent BCS between 12:00am-3:25pm. Patients were stratified into two groups: those who underwent re-excision to achieve clear margins and those who did not. Overall survival rates were compared between the two groups using Kaplan- Meier analysis and Cox proportional hazards models, adjusting for potential confounding variables such as age, tumor stage, hormone receptor status, and adjuvant therapy. Additionally, subgroup analyses were performed to assess the impact of re-excision on overall survival among different patient populations. Our findings provide valuable insights into the role of re-excision in improving overall survival outcomes among breast cancer patients undergoing BCS, with implications for clinical decision-making and patient counseling.