ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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  • Mini Review   
  • J Infect Dis Ther 2017, Vol 6(2): 356
  • DOI: 10.4172/2332-0877.1000356

Impact of Antibiotic Use in Patient Colonization with Multidrug-resistant Organisms

Damaceno QS*
Department of Microbiology, Universidade Federal de Minas Gerais, Hospital Universitário Ciências Médicas, Brazil
*Corresponding Author : Damaceno QS, Department of Microbiology, Universidade Federal de Minas Gerais, Hospital Universitário Ciências Médicas, Brazil, Tel: +55(31)32998233, Email: qsdamasceno@gmail.com

Received Date: Feb 26, 2018 / Accepted Date: Mar 14, 2018 / Published Date: Mar 19, 2018

Abstract

There are some variables associated with multidrug-resistant organisms (MDRO) establishment success in healthcare settings and infection outcomes such as long-time use of antibiotics, immunosuppression, medical devices, loss of skin integrity, time of permanence of patients in ICUs and microorganism virulence. Our aim was to review the impact of antimicrobial use in patients’ colonization with MDRO. In fact, gene encoding resistance can be detected even in commensal microbiota. Some analysis using DNA sequencing to evaluate microbiomes has confirmed the impact of antibiotic use in microbiota leading to the emergence of potential pathogens. Conversely, the decreased use of a specific antibiotic can lead to loss of resistance.

Keywords: Bacterial drug resistance; Normal microbiota; Antimicrobial use; Inpatients

Citation: Damaceno QS (2018) Impact of Antibiotic Use in Patient Colonization with Multidrug-resistant Organisms. J Infect Dis Ther 6: 356. Doi: 10.4172/2332-0877.1000356

Copyright: ©2018 Damaceno QS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium.

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