Abstract

Obstructive respiratory tract disorders encompass a diverse spectrum of conditions affecting the airways, ranging from chronic obstructive pulmonary disease (COPD) to asthma and bronchiectasis. These disorders are characterized by varying degrees of airway inflammation, structural changes, and progressive airflow limitation. Among the pathophysiological mechanisms underlying disease progression, airway remodeling plays a pivotal role. This article reviews current understanding of airway remodeling in obstructive respiratory tract disorders, focusing on its impact on disease progression and therapeutic implications.