Abstract

Hereditary factors play a significant role in the development of bone cancer, offering valuable insights into its etiology and pathogenesis. This article provides an overview of the genetic predisposition to bone cancer, highlighting key syndromes associated with increased risk and discussing recent advances in our understanding of the molecular mechanisms underlying tumor development. The clinical implications of hereditary factors in bone cancer, including risk assessment, early detection strategies, and personalized treatment approaches, are also explored. Finally, the challenges and future directions in the field of hereditary bone cancer research are discussed, emphasizing the importance of interdisciplinary collaboration and continued efforts to translate genetic insights into improved patient care.