Abstract

Crystallography stands at the forefront of modern drug design, offering unparalleled insights into the molecular structures that underpin biological processes and disease mechanisms. This paper explores the transformative role of crystallography in drug development, emphasizing its ability to decipher intricate atomic arrangements of drug-target complexes. By revealing precise interactions at the atomic level, crystallography guides the rational design of novel therapeutics with enhanced efficacy and specificity. Moreover, advancements in crystallographic techniques, such as X-ray crystallography and cryo-electron microscopy, have expanded the scope and precision of structure-based drug design, accelerating the discovery of promising drug candidates. This abstract highlights how harnessing crystallography enables researchers to address complex biomedical challenges, ultimately paving the way for breakthroughs in modern medicine.