Abstract

Antisocial behavior in adolescents is commonly acknowledged as a neurodevelopmental challenge. Despite the growing body of knowledge concerning the neurobiology of persistent antisocial behavior, conduct disorders, and psychopathic traits, there is a notable gap in the application of this knowledge within clinical practice.

This review aims to provide a comprehensive overview of recent research findings on the neurobiology of antisocial behavior in adolescents and to explore potential avenues for translating this knowledge into youth forensic clinical practice. The review begins with a synthesis of recent literature encompassing genetics, neuroimaging, neuropsychology, neurophysiology/neuroendocrinology, and their associations with antisocial behavior in adolescents. Subsequently, the implications of these findings for diagnostic procedures, risk assessment, and treatment strategies are examined. Finally, the review advocates for an integrated biopsychosocial approach in future research endeavors, emphasizing the need for translational efforts in the field of forensic child and adolescent psychology and psychiatry