Glyphosate Intoxication Presenting with Bilateral Pneumothoraces and Boerhaave?s Syndrome: A Case Report
Received Date: Feb 11, 2021 / Accepted Date: Feb 25, 2021 / Published Date: Mar 01, 2021
Abstract
In this case report we present a young, healthy male, presenting to hospital 5 days after ingesting Roundup®, a glyphosate-containing herbicide. His main complaints included haematemesis, pleuritic chest pain and dyspnoea. Initial assessment revealed a Left Pneumothorax (PTX) for which an intercostal drain (ICD) was inserted. On further evaluation he had Acute Kidney Injury (AKI), toxic hepatitis and developed a right sided PTX on the third day of admission. Pneumomediastinum was identified on follow-up chest x-ray (CXR). These findings, in conjunction with his presenting complaints and the clinical finding of Hamman’s crunch on auscultation, a diagnosis of Boerhaave’s syndrome was postulated, which was confirmed on contrast enhanced Computed Tomography (CT) of the chest with swallow. A brief overview of glyphosate toxokinetics and Boerhaave’s syndrome is provided.
Keywords: Glyphosate; Boerhaave’s syndrome; pneumomediastinum; Oesophageal perforation
Citation: Beyers BD, Landman FR, Jacobs SJ, Beyers A, Rodriguez GLN, et al (2021) Glyphosate Intoxication Presenting with Bilateral Pneumothoraces and Boerhaave’s Syndrome: A Case Report. Toxicol:Open Access 7:154. Doi: 10.4172/2476-2067.1000154
Copyright: © 2021 Beyers BD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.