Abstract

This study aims to estimate the global prevalence of fatty liver disease (FLD) among adults who are obese or overweight due to metabolic dysfunction. FLD, characterized by excessive fat accumulation in the liver, is closely associated with obesity and metabolic syndrome. Using data from international health surveys and epidemiological studies, we conducted a comprehensive meta-analysis to assess the prevalence rates of FLD across different regions and demographic groups. Key findings reveal a substantial burden of FLD among obese adults worldwide, with variations observed based on geographical location, socioeconomic factors, and healthcare access. The study underscores the urgent need for global strategies to address the rising prevalence of FLD and its associated health risks, including liver cirrhosis and hepatocellular carcinoma. Implications for public health include targeted interventions to promote weight management, improve metabolic health, and enhance early detection and treatment of FLD to mitigate its progression and reduce morbidity and mortality globally. Continued surveillance and research are essential to monitor trends, inform policy development, and optimize healthcare resources for managing FLD in obese populations.