Journal of Alzheimers Disease & Parkinsonism
Open Access

Research Article

Glaucoma in Patients with Parkinson’s Disease

Nowacka Barbara^1*, Lubiński Wojciech¹, Honczarenko Krystyna², Potemkowski Andrzej³ and Safranow Krzysztof⁴

¹Department of Ophthalmology of the Pomeranian Medical University, Szczecin, Poland

²Department of Neurology of the Pomeranian Medical University, Szczecin, Poland

³Department of Clinical Psychology of the University of Szczecin, Szczecin, Poland

⁴Department of Biochemistry and Medical Chemistry of the Pomeranian Medical University, Szczecin, Poland

Corresponding Author:

Barbara Nowacka
Department of Ophthalmology of the Pomeranian Medical University
Powstancow Wlkp 72 70-111
Szczecin, Poland
Tel: 0048 607 488 169
E-mail: barbara_nowacka@vp.pl

Received date: November 25, 2016; Accepted date: January 16, 2017; Published date: January 23, 2017

Citation:Nowacka B, Lubinski W, Honczarenko K, Potemkowski A, Safranow K (2017) Glaucoma in Patients with Parkinson’s Disease. J Alzheimers Dis Parkinsonism 7:301. doi:10.4172/2161-0460.1000301

Copyright: © 2017 Barbara N, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Objective: To determine if patients with Parkinson’s disease (PD) have an increased risk of glaucoma. Materials and methods: The cross-sectional case-control study. One hundred consecutive patients (196 eyes) with idiopathic PD and a control group consisting of 100 healthy matched for age and sex patients (196 eyes) underwent a complete ophthalmological examination of both eyes, including assessment of slit lamp examination of the eye anterior segment and fundus, intraocular pressure and evaluation of the peripapillary retinal nerve fiber layer (RNFL) thickness. Participants were also evaluated in terms of perfusion pressures in the eyes. Results: The frequency of glaucoma was higher in eyes of PD patients in comparison to controls (16.33% vs. 6.63%; p=0.004) and intraocular pressure was significantly lower (16.88 ± 3.18 vs. 17.76 ± 3.21 mm Hg; p=0.009). Systolic and diastolic blood pressure, as well as calculated perfusion pressures did not differ significantly between PD and control group with exception of higher diastolic perfusion pressure in PD patients’ eyes. The retinal fiber layer thickness did not significantly differ between investigated no-glaucoma groups, but revealed significant reduction in superior and inferior quadrant in glaucoma PD patients. Conclusion: PD patients have increased risk of glaucoma.

Keywords