Abstract

This study presents the complete genome sequence of a Circovirus strain isolated from a pigeon found in the lymphocyte-depleted bursa of Fabricius of a Common Raven. The isolation occurred in a wildlife rehabilitation setting, where the raven exhibited signs of immunosuppression. Using next-generation sequencing, we characterized the Circovirus genome, revealing a total length of approximately 2,000 base pairs. Bioinformatic analysis indicated the presence of typical circoviral features, including two major open reading frames (ORFs) that encode for the replicase and capsid proteins. Phylogenetic analysis positioned this strain within the Circovirus genus, showing close genetic relatedness to previously identified pigeon and avian circoviruses. The findings suggest potential interspecies transmission of Circovirus between pigeons and ravens, raising concerns about the implications for avian health and biodiversity. This research contributes to the understanding of Circovirus epidemiology and the potential impact on immunocompromised avian species. Further studies are warranted to explore the pathogenicity and transmission dynamics of this Circovirus strain in wild and domestic birds.