Abstract

Already for a long time, it is clear that “Nothing in Biology Makes Sense Except in the Light of Evolution” [1]. This is more than true and crucial also for the human and generally mammalian genome that represents the highest structural and functional complexity with the most finely tuned spatial-temporal regulation, we can imagine. Hence, to understand this immense complexity of human and mammalian genome and above all the pathological conditions, it is necessary to view them in a broader, evolutionary, context. Moreover, it is necessary to view also the human genome as a result of hundreds of millions of years long evolution from our fish-like ancestors, via tetrapod amphibians and reptiles, and finally towards mammals. Therefore, to make the picture clearer and complete it is essential to explore the genomic complexity in mammalian as well as non-mammalian vertebrates. This is one of the main objectives of this newly launched journal, Journal of Genome.

Keywords: Genome, Evolutionary biology ,Epigenomics