Abstract

Nuclear Magnetic Resonance (NMR) spectroscopy has emerged as a versatile analytical technique with wideranging applications, from drug design to metabolomics. This abstract highlights the multifaceted roles of NMR in various fields of research. In drug design, NMR provides critical insights into the structural and dynamic properties of biological targets, enabling the rational design and optimization of therapeutic agents. By elucidating protein-ligand interactions and binding kinetics, NMR facilitates a deeper understanding of drug efficacy and selectivity. In the realm of metabolomics, NMR serves as a powerful tool for the identification and quantification of metabolites in biological samples, allowing researchers to explore metabolic pathways and disease states. Recent advancements in NMR technology, including improved sensitivity and multidimensional techniques, have further enhanced its capability to analyze complex mixtures and provide detailed metabolic profiles. This review emphasizes the significance of NMR spectroscopy as a crucial instrument in both drug discovery and metabolomics, showcasing its ability to bridge structural biology and systems biology. Through its diverse applications, NMR continues to contribute to our understanding of biochemical processes and the development of novel therapeutic strategies.