Journal of Gastrointestinal & Digestive System
Open Access

Case Report

First Case of Liver Abscess with Endogenous Endophthalmitis due toNon- K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268

¹Department of Infectious Diseases, Tokyo Women’s Medical University, Tokyo, Japan

²Department of Ophthalmology, Tokyo Women’s Medical University, Tokyo, Japan

³Faculty of Medicine, Department of General Medicine, Juntendo University, Tokyo, Japan

*Corresponding Author:

Ken Kikuchi, M.D. Ph.D.
Department of Infectious Diseases
Tokyo Women’s Medical University
8-1 Kawada-cho
Shinjuku-ku, Tokyo 162-8666, Japan
Tel: +81-3-3813-3111
Fax: +81-3-5684-7830
E-mail: kikuchi.ken@twmu.ac.jp

Received date: December 9, 2015; Accepted date: January 22, 2016; Published date: January 29, 2016

Citation: Hirai Y, Asahata-Tago S, Ainoda Y, Fujita T, Uzawa Y, et al. (2016) First Case of Liver Abscess with Endogenous Endophthalmitis due toNon-K1/K2 Serotype Hypermucoviscous Klebsiella pneumoniae Clone ST268. J Gastrointest Dig Syst 6:383. doi:10.4172/2161-069X.1000383

Copyright: © 2016 Hirai Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

The hypermucoviscous (hv) Klebsiella pneumoniae (KP) can cause invasive liver abscess syndrome (ILAS) including endophthalmitis dominantly in eastern Asia. We report a 80-years old woman who diagnosed with invasive liver abscess syndrome due to K. pneumoniae (KP) non-K1/K2 hvKP multi-locus sequence type ST268 by DNA amplification methods isolated from blood culture. Soon she developed endogenous endopththalmitis and immediately right vitrectomy was performed. Although intravenous 2g of ceftriaxone (CTRX) was administrated, total enucleation of right eyeball had performed due to orbital cellulitis and necrosis of eye ball finally. To find complication (i.e. endophthalmitis) with caution and to select antimicrobial agents with sufficient penetration to CNS (i.e. ceftriaxone) is needed in a patient with severe hvKP infection. Usually ILAS is caused by K1/K2 hvKP. However, to our knowledge, this is a first report of ILAS with endophthalmitis and orbital cellulitis due to non-K1/K2 hvKP ST268.

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