Abstract

Neuropathic pain presents a complex clinical challenge characterized by abnormal sensory processing within the nervous system. This abstract delves into the pharmaceutical perspective of neuropathic pain management, providing insights into current treatment modalities, emerging therapies, and challenges faced in clinical practice. Pharmacotherapy remains a cornerstone of neuropathic pain management, with drugs targeting various pain pathways and mechanisms, including antidepressants, anticonvulsants, and topical agents. Emerging therapies, such as NMDA receptor antagonists, cannabinoids, and gene therapy, offer promising avenues for novel treatment approaches. However, challenges such as variable treatment responses, medication side effects, and the lack of universally effective treatments underscore the need for personalized and multimodal approaches to pain management.