Abstract

This study delves into the relationship between obesity and aging by examining their impact on DNA metabolism. Obesity, a complex metabolic disorder, has been implicated in accelerating the aging process and increasing the risk of age-related diseases. DNA metabolism, encompassing processes such as DNA replication, repair, and epigenetic modifications, plays a crucial role in maintaining genomic integrity and regulating cellular functions. However, the interplay between obesity and DNA metabolism in the context of aging remains poorly understood. By elucidating this relationship, we aim to gain insights into the molecular mechanisms underlying obesity-associated aging and identify potential targets for intervention. Through a comprehensive review of existing literature and experimental studies, we explore how obesity influences various aspects of DNA metabolism and contributes to age-related changes at the molecular level. Additionally, we discuss the implications of these findings for understanding the pathophysiology of obesity-related diseases and developing novel therapeutic strategies to promote healthy aging.