Exploring Biodegradable Scaffolds for Personalized Cancer Immunotherapy: Nanomaterial Approaches to Tumor Microenvironment Modulation
*Corresponding Author: Subasini Oghenemaro, Faculty of Pharmacy, Pharmacology Department, Tishk International University, Iraq, Email: OghenemaroSUBASINI999@gmail.comReceived Date: Nov 05, 2024 / Published Date: Nov 29, 2024
Citation: Subasini O (2024) Exploring Biodegradable Scaffolds for Personalized Cancer Immunotherapy: Nanomaterial Approaches to Tumor Microenvironment Modulation. J Biotechnol Biomater, 14: 416.
Copyright: © 2024 Subasini O. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract
Personalized cancer immunotherapy has emerged as a transformative approach to combat cancer, focusing on tailoring treatments to individual patients. A critical challenge lies in effectively modulating the tumor microenvironment (TME) to overcome immune suppression and enhance therapeutic efficacy. Biodegradable scaffolds, particularly those incorporating advanced nanomaterials, offer innovative solutions for precise TME modulation. These scaffolds enable localized and sustained delivery of immunomodulatory agents, while their biodegradable nature minimizes long-term side effects. This review explores cutting-edge nanomaterial-based scaffolds designed for personalized cancer immunotherapy, highlighting their role in reshaping the TME, promoting immune activation, and advancing patient-specific therapeutic strategies. Future directions and translational challenges are also discussed, emphasizing the potential of these approaches to revolutionize cancer treatment.