Clinical Pharmacology & Biopharmaceutics
Open Access

Exosome-Mediated Drug Delivery: Enhancing Targeted Therapy for Cancer and Neurodegenerative Diseases

Chandrasiri Waliwita^*

Department of Cikitsa (Ayurveda Medicine), Gampaha Wickramarachchi Ayurveda Institute, Sri Lanka

Received Date: Nov 01, 2024 / Published Date: Nov 29, 2024

Citation: Chandrasiri W (2024) Exosome-Mediated Drug Delivery: Enhancing Targeted Therapy for Cancer and Neurodegenerative Diseases Clin Pharmacol Biopharm, 13: 516.

Copyright: © 2024 Chandrasiri W. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

To read the full article Peer-reviewed Article PDF | Peer-reviewed Full Article

Exosomes, nanoscale extracellular vesicles secreted by various cell types, have emerged as promising tools for drug delivery due to their intrinsic biocompatibility, low immunogenicity, and natural ability to target specific cells. This review explores the potential of exosome-mediated drug delivery for enhancing targeted therapies in cancer and neurodegenerative diseases. By leveraging the inherent characteristics of exosomes, including their ability to cross biological barriers such as the blood-brain barrier, researchers are developing innovative methods to load therapeutic agents into exosomes for precise delivery. Recent advancements in engineering exosomes for enhanced targeting, stability, and payload capacity are discussed, alongside challenges related to large-scale production, standardization, and clinical translation. The promising results from preclinical and early clinical studies highlight the potential of exosomes as a transformative platform for precision medicine in treating complex diseases.