Review Article
EV71, A Virus with Complicated Pathogenesis in the CNS
Min Feng and Qihan Li* | ||
Institute of Medical Biology, Chinese Academy of Medicine Sciences & Peking Union Medical College, Kunming, 650118, China | ||
Corresponding Author : | Qihan Li Institute of Medical Biology Chinese Academy of Medicine Sciences and Peking Union Medical College, China Tel: 86-871-68335905 Fax: 86-871-68334483 E-mail: imbcams.lq@gmail.com |
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Received June 02, 2014; Accepted July 15, 2014; Published July 20, 2014 | ||
Citation: Feng M, Li Q (2014) EV71, A Virus with Complicated Pathogenesis in the CNS. J Infect Dis Ther 2:153. doi:10.4172/2332-0877.1000153 | ||
Copyright: © 2014 Feng M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | ||
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Abstract
Fatal cases of hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) infection are characterized by inflammatory damage to the central nervous system (CNS) with slight degeneration of nerve cells. Here, we review several studies that identify potential host factors and possible mechanisms of neuropathogenesis of EV71 infection.