Abstract

Epigenetic modulation, which involves heritable changes in gene expression without altering the DNA sequence, plays a significant role in the development and progression of cardiovascular disease (CVD). This paper, Epigenetic Modulation and Cardiovascular Disease, explores the impact of epigenetic modifications on cardiovascular health, highlighting how these mechanisms influence disease onset, progression, and treatment outcomes. Epigenetic modifications such as DNA methylation, histone modification, and non-coding RNA regulation are crucial in controlling gene expression involved in cardiovascular processes. These modifications can affect various aspects of cardiovascular biology, including inflammation, vascular function, and myocardial remodeling. Abnormal epigenetic patterns have been linked to common cardiovascular conditions, including atherosclerosis, hypertension, heart failure, and myocardial infarction.