Abstract

Several liposome-based formulations received approval by the U.S. Food and Drug Administration and European Medicines Agency, with many others in clinical trials. Liposomes have several advantages, including improved pharmacokinetic properties of the encapsulated drug, reduced systemic toxicity, extended circulation time, and targeted disposition in tumor sites due to the enhanced permeability and retention mechanism. However, it is worth noting that despite their efficacy in treating various cancers, liposomes still have some potential toxicity and lack specific targeting and disposition. The focus of this review will be to highlight recent developments in liposome-based therapeutics that are relevant for veterinary medicine. This review will recap recent and ongoing research on liposome-based therapeutics in cancer therapy, vaccine delivery, and pain management in species of veterinary and agricultural relevance.