Abstract

Drug bioavailability studies are essential in understanding how drugs are absorbed, distributed, metabolized, and excreted within the body, influencing their therapeutic efficacy and safety. This article explores recent advancements and emerging trends shaping bioavailability research. Topics include advanced analytical techniques like LC-MS/MS and NMR spectroscopy, personalized medicine approaches integrating pharmacogenomics, nanotechnology in drug delivery systems, the Biopharmaceutics Classification System (BCS), and physiologically-based pharmacokinetic (PBPK) modeling. These trends promise to enhance drug development processes, optimize formulation strategies, and improve treatment outcomes across various therapeutic areas